食管癌中医证型分布与中药治疗研究进展-刘洁

35720177CHINESEAＲCHIVESOFTＲADITIONALCHINESEMEDICINEVol．35No．7Jul．20171772DOI10．13193/j．issn．1673-7717．2017．07．0375100105。。、、、。、、、、。Ｒ735A1673-7717201707-1772-03ＲesearchProgressofTCMSyndromeTypesandTreatmentofEsophagealCancerLIUJieLILipingZHAOYagangDepartmentofGastroenterologyGuangzhouGeneralHospitalofGuangzhouMilitaryCommandGuangzhou510010GuangdongChinaAbstractWecollectedthetraditionalChinesemedicinesyndromesofesophagealcancerforthepastfiveyearsandsystematicallysummarizethecurrentresearchprogress．CurrentlythemortalityrateofesophagealcancerishighbutwiththedeepeningofitsresearchwehavemadesomeprogressonTCMsyndromedistributionandtraditionalChinesemedicinetreatment．Esophagealsyndromesaredividedintophlegm－Qiinter－obstructiontypephlegmandbloodstasistypetoxicheatandYindeficiencytypeQideficiencyandYangweaknesstypeandspleendeficiencyandQistagnationtype．Chinesemedicinesyndromedifferentiationcanimprovethetherapeuticeffectofesophagealcancer．PaclitaxelVi-texinbaohuosideITetrandrineandTripterygiumwilfordiicanbeusedforclinicaldiagnosisandtreatmentofesophagealcancerinordertoimprovethetherapeuticeffect．KeywordsesophagealcancerPaclitaxelVitexinbaohuosideITetrandrineTripterygiumwilfordii2017－02－12813021641990－。1961－、、。E-mailyagang78@163．com。6150%2510%。“”《·》“”、。3456。5。1、、、。7《》8《》、、、。9。、、、4。10、、、。11、、、、。13、、、、。12、、、4。134、、、277135720177CHINESEAＲCHIVESOFTＲADITIONALCHINESEMEDICINEVol．35No．7Jul．20171773。14、、、。15、、。、、、、、、、。。。、。。2、。、、、、。《》。、、、、、、、、、、。16－19。“”、“”“”“”20－21。、、、。22、、、、、。《》、、、、《》《》。、、。、、、。、、23、2425、2627。、、、《》。－Ⅰ。－Ⅰ。－Ⅰ28－2930。、、。、、、、。《》、。《》。。、、、、、31。323334。《》、、、、、、。、、、35。、3637。3、、、、、、4。。。、、、377135720177CHINESEAＲCHIVESOFTＲADITIONALCHINESEMEDICINEVol．35No．7Jul．20171774、22、、、－Ⅰ－Ⅰ。－Ⅰ28－2930、、36。、、、、、、。。1HongmeiZengＲongshouZhengSiweiZhangetal．Esophage-alcancerstatisticsinChina2011Estimatesbasedon177cancerregistriesJ．ThoracCancer201672232－237．2ArdeleanuVFrancuLGeorgescuC．Neoangiogenesis．Assess-mentinEsophagealAdenocarcinomasJ．IndianJSurg201577Suppl3971－976．3．J．20131134169－170．4．TPQOLKPSJ．201028112455－2457．5．J．20112992151－2152．6．J．20143261527－1531．7．M．2003214－217．8．M．2007144－174．9．J．200840865－66．10．J．20115210821－822．11．J．2012627655－657．12·．TNF－α、IL－6J．2012394595－597．13．J．2014827150．1460J．2015131472－73．15．J．2016363267－270．16．36J．201329121776－1778．17．60J．20141142－43．18J．HoningJ．K．SmitC．T．Muijs．Acomparisonofcarbo-platinandpaclitaxelwithcisplatinumand5－fluorouracilinde-finitivechemoradiationinesophagealcancerpatientsJ．AnnOncol2014253638－643．19Yi－FuHeChu－ShuJiBingHu．AphaseIIstudyofpacli-taxelandnedaplatinasfront－linechemotherapyinChinesepa-tientswithmetastaticesophagealsquamouscellcarcinomaJ．WorldJGastroenterol201319355910－5916．20．M．201286－90．21．M．201245－48．22．J．2015403382－387．23．J．2013103535－42．24．J．2015271228－31．25．J．201333184472－4475．26．J．201324197－199．27FANGANSHUHUAWANGQINGQINGTIAN．EffectsoforientinandvitexinfromTrolliuschinensisonthegrowthandapoptosisofesophagealcancerEC－109cellsJ．OncolLett20151042627－2633．28．1J．．2009368635－638．29．－IEca－109Wnt/p－cateninJ．2011421124－126．30．－1Eca－109J．201117313－5．31．J．201334275－79．32．Eca－109J．2011162119－123．33．J．2015282129－131．34．SurvivinCaspase－3J．2013366986－988．35．J．2013403416－418．36．J．2015673341－347．37．J．201518364496－4500．4771