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MalnutritioninPatientsWithCancer:ComparisonofPerceptionsbyPatients,Relatives,andPhysicians—ResultsoftheNutriCancer2012StudyJournalofParenteralandEnteralNutritionIF：3.517Publication:Jan20171研究背景及目的01研究结果03研究对象及方法02讨论及总结04THEMAINCONTENTS22020/9/171第部分研究背景及目的32020/9/17研究背景及目的01Malnutritionincreasestheriskoftreatmenttoxicityandimpairsoutcomesofpatientswithcancer.Earlynutritioninterventionsarerecommendedinproperlyidentifiedpatientsforimprovingtreatmenttoleranceandpatientsurvival.Underestimationofmalnutritionremainsasignificantissuesinceearlyrecognitionofmalnutritionmayallowforearlyoptimizationofnutritioninterventionstosupportpatientsduringtreatment.Patientself-screeningformalnutritionhasbeenreportedasfeasibleincancer,andrelativesmayalsoprovideexternalinformationonnutrition.42020/9/17研究背景及目的01questions:Whetherpatientswithcancerand/ortheirrelativesareawareofmalnutritionandcouldimprovetheefficacyofnutri-tioninterventionsisunclear.However,thesubjectiveawarenessofmalnutritionbythepatients,theirrelat-ives,andphysicianshasnotyetbeenassessedorcompared.52020/9/17研究背景及目的01ObjectiveTocomparethevalidateddefinitionofmalnutritionwiththeperceptionsofnutritionstatusbypatients,relatives,andphysicians.Tofindouttheriskfactorsofmalnutrition.62020/9/172第部分研究方法及对象72020/9/1702研究方法及对象MethodsTheNutriCancer2012multicentriccross-sectionalsurveywasconductedon1predefinedday.Thesurveywasconductedin283departmentsofprivateorpublichospitalsin36citiesinFranceonOctober9,2012,andincluded2197patients.Eachincludedpatienthadtocompleteaquestionnaire.Theatt-endingphysicianonthedayofthevisitwasincluded,aswellastheclosestrelative,whoalsoreceivedquestionnairestocom-plete.82020/9/1702研究方法及对象Inclusioncriteriapatientsdiagnosedwithcancer,aged≥18years,andwillingtocompleteaquestionnaire.Malnutritionwasidentifiedasfollows:weightloss≥5%within1monthor≥10%within6months,abodymassindex(BMI)≤18.5kg/m2inpatientsaged70yearsor≤21kg/m2inpatientsaged≥70years,albu-minemia(whenavailable)35g/Linpatientsaged≥70years.92020/9/173第部分研究结果102020/9/17研究结果03112020/9/17研究结果03Malnutritionprevalenceandstatisticalanalysis:Overall,826patientsweremalnourished(39%;95%confidenceinterval[CI],37–41),withahigherpre-valenceinpatientswithliverandpancreaticcancers122020/9/17研究结果03Malnutritionwasidentifiedin40%,40%,and31%ofpatientsininitialevolution,relapse,orremission,respectively,and27%ofpatientswithlocaldiseasestage.132020/9/17研究结果03Prevalenceofmalnutritionwas39%.Physiciansoverestimatedmalnutrition(44%),whereaspatientsandrelativesunderes-timatedit(24%and25%,respe-ctively,P.001).142020/9/17研究结果03Accordingtoquest-ionnaires,57%ofpatientsand61%ofrelativesreportedalowerfoodintake,m-ainlybecauseofGIsymptoms.152020/9/17研究结果03Nutritionint-erventionswererecalledandwerem-orefrequentinmalnouri-shedpatients162020/9/174第部分讨论及总结172020/9/17讨论及总结04Thisstudyconfirmedthehighprevalenceofmalnutrition(39%)inpatientswithcancer.Thepercentageobtainedisslightlyhigherthanthe30.9%foundinapreviousstudybyPressoiretal[7]andlowerthanthe43.5%and52%reportedbyNourissatetal[8]andSeguraetal,[9]respectively.Oneexplanationcouldbethedifferentproportionsofpa-tientswithGIlocations:32%inourstudycomparedwith17%and34%inthestudiesbyPressoiretal[7]andNourissatetal,8respectively,whileinthestudybySeguraetal,9theproportionofpatientswithpancreaticandlungcancerswashigher.01182020/9/17讨论及总结0402Patientsandrelativesunderestimatedmalnutritionwhilephysiciansoverestimatedit,indicatingalowawarenessofpatientsandrelativesregardingmalnutritionincancer.Furtherstudiesareneededtoimprovetheawarenessofmal-nutritioninpatientsandtheirrelativesaswellastheefficacyofnutritioninterventions.192020/9/17讨论及总结04请老师同学指正批评时间：2017.3.15Thanksforyourattention202020/9/17